Welcome to my site, I hope you will find it to be a helpful resource. I currently work as a lecturer in Dundalk IT’s Applied Sciences department. I love what I do. It’s my dream job, but as you will see below, it has taken a long career path to get to this position. After a lengthy and productive stay at NUI Galway (1995-2007), followed my time working in Industry, I managed to obtain my current position where I have been working for 5 years now. I hope this site will assist you in learning about careers and options, keeping up-to-date with science news and each other via social networking, in addition to acting as a virtual learning environment for students currently enrolled in my classes. Science has always been my passion. I have been very fortunate to have worked with incredible people during each stage of my career to get me to where I am now. Every day is an opportunity to improve and learn….so make today count!
Outside of work, I believe it is critical to have a balance. I am very passionate about photography and taking images of landscapes around Ireland is something I could do all day. More recently, the majority of my free time is spent with my wife and our amazing children, Doireann & Senan.
For further information on my background, please click on any of the links below:Expertise Career History Education Publications
- Masters in Arts in Learning & Teaching. Awarded Oct 2013.
- 7 years Lecturing experience with module design and course development.
- Industry experience with ICON Clinical Research (Dublin).
- 5 years cell culture experience.
- PhD in Developmental Genetics / Biochemistry.
- 5 Year post-doc with targeted gene knock-out and knock-in strategy development and implementation in the field of DNA damage/Cancer research.
- Experience in International labs: (Scotland (Beatson, Glasgow, Gillespie lab), France (IGBMC, Strasbourg, Strähle lab) and USA (UCSF, Stainier lab).
- Publications in peer reviewed journals and oral presentations at international conferences.
- Sept 2009 – Present: Lecturer – Biochemistry & Molecular Biology, Dept. of Applied Sciences, Dundalk Institute of Technology; Lecture Courses: Molecular biology, Biochemistry, Immunology, Upstream processing, Biotherapeutics, Y3 Project, Y4 Project.
- Mar 2009 – Aug 2009 – Senior Study Lead, Biometrics & Data Management, ICON Clinical Research
- Apr 2008 – Mar 2009 – Manager, EU & Asia-Pacific Proposals, Business Development Manager, ICON Clinical Research
- Jan 2003 – Sept 2007 – Post-Doctoral Research Scientist, NUI Galway; Supervisor: Professor Noel F. Lowndes. The basis of my post-doctoral research was to understand the role of a particular factor in a cell’s response to DNA damage. Failure to sense and repair damage to the DNA backbone in our cells is a main cause of cancer. See http://www.chromosome.ie
- 2013 – Masters in Learning & Teaching (First Class Honours, Awarded Oct 2013)
- 2012-2013 – Diploma in Learning & Teaching, Dundalk Institute of Technology (progressed to Masters)
- 2011-2012 – Certificate in Learning & Teaching, Dundalk Institute of Technology (progressed to Diploma)
- 1999 – 2003 Ph.D Biochemistry/Developmental Biology, National University of Ireland, Galway; Supervisors: Dr. Lucy Byrnes & Dr. Maura Grealy. My PhD research revolved around the search for novel genes that were expressed for the first time at a particular stage of embryo development known as the midblastula transition in the zebrafish model system. My research led to the identification of many target genes including a novel gene, named nanor.
- July 2001 – December 2001: Visiting Scholar at UCSF, San Francisco, USA at University of California, San Francisco; As part of my Ph.D research, I received a scholarship to travel to San Francisco. I was fortunate to obtain a position in the lab of Didier Stainier where I worked on understanding embryo development in the zebrafish model system.
1. Bree RT, Gallagher G. (2016). Using Microsoft Excel to code and thematically analyse qualitative data: a simple, cost-effective approach. The All Ireland Journal of Teaching and Learning in Higher Education. 8(2)
Engaging Learning And Addressing Over-assessment In The Science Laboratory: Solving A Pervasive Problem. The All Ireland Journal of Teaching and Learning in Higher Education. 6(3).. (2014).
3. Nakahara M, Sonoda E, Nojima K, Sale JE, Takenaka K, Kikuchi K, Taniguchi Y, Nakamura K, Sumitomo Y, Bree RT, Lowndes NF, Takeda S. Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes. PLoS Genet. 2009 Jan;5(1).
4. Bree RT, Lai X-Y, Canavan LE & Lowndes NF. Comparisons Between DT40 Wild Type and Cre1 Cells as Suitable Model Systems for Studying the DNA Damage Response. Cell Cycle, vol 6; issue: 18, 2007.
5. Bree RT*, O’Boyle S* (equal contribution), McLoughlin S, Grealy M, Byrnes L. Identification of zygotic genes expressed at the midblastula transition in zebrafish. Biochem Biophys Res Commun. Jun 29;358(2):462-8. 2007 (* Equal Contribution).
6. Nakamura K, Sakai W, Kawamoto T, Bree RT, Lowndes NF, Takeda S, Taniguchi Y. Genetic dissection of vertebrate 53BP1: a major role in non-homologous end joining of DNA double strand breaks. DNA Repair (Amst) Jun 10;5(6):741-9. 2006.
7. Bree RT, McLoughlin S, Jin SW, McMeel OM, Stainier DY, Grealy M, Byrnes L. nanor, a novel zygotic gene, is expressed initially at the midblastula transition in zebrafish. Biochem Biophys Res Commun. Aug 5;333(3):722-8. 2005.
8. Bree RT, Neary C, Samali A, Lowndes NF. The switch from survival responses to apoptosis after chromosomal breaks. DNA Repair (Amst), Aug-Sep;3(8-9):989-95. 2004.
9. van den Bosch M, Bree RT, Lowndes NF. The MRN complex: coordinating and mediating the response to broken chromosomes. EMBO Reports. Sep;4(9):844-9. 2003.
10. Bree RT, Stenson C, Grealy M, Byrnes L, Gorman A, Samali A. Cellular longevity: role of apoptosis and replicative senescence. Biogerontology, vol. 3 issue 4. 2002.
11. Brabazon, ED, Bree RT, Carton MW, Grealy M, Byrnes L. Cyclin-dependent kinase 8 is expressed both maternally and zygotically during zebrafish embryo development. Biochimica et Biophysica Acta, Jun 7;1576(1-2):203-8. 2002.